Fig. 2: Top motif hits of DNA motif associated with Strip2 identified via SeqPos motif tool analysis.
From: Epigenetic mechanisms of Strip2 in differentiation of pluripotent stem cells
A The five best hits are shown. Out of five motifs, motif 1 and 5 have matches to ZNF274 and SNAI1, EXB1 and MESP1. B Motifs significantly enriched in Strip2 mESCs were identified by analysis of motif enrichment (AME). C Luciferase expression in Strip2 + -ESCs show that the absence of Strip2 (Strip2 − -ESCs) further stimulates expression, while Transient overexpression of Strip2 reduces expression to baseline levels. Average fold change of relative luciferase units (RLU) vs empty vector (n = 3, mean ± SD).
