Fig. 3: Overview of principal component analysis and differentially expressed gene analysis with the molecular mechanisms at four time-points. | Cell Death Discovery

Fig. 3: Overview of principal component analysis and differentially expressed gene analysis with the molecular mechanisms at four time-points.

From: Stepwise molecular mechanisms responsible for chemoresistance in bladder cancer cells

Fig. 3

A The principal component analysis (PCA) of the GRC1 cell line (n = 16) is based on the 1869 genes associated with molecular mechanisms (CPM > 1 and S.D > 1). B Gene expression patterns of 1869 genes and enriched biological characteristics at four time-points. The colors in the heatmap reflect relatively high (red) and low (blue) expression (left panel). Results of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) enrichment analysis of four time-points (right panel).

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