Fig. 2: Induction of stem cell markers by UM171 in HEL cells. | Cell Death Discovery

Fig. 2: Induction of stem cell markers by UM171 in HEL cells.

From: UM171 cooperates with PIM1 inhibitors to restrict HSC expansion markers and suppress leukemia progression

Fig. 2

A–D The Bi-potential Megakaryocytic Erythroid Progenitor (MEP) derived HEL cell line was treated with UM171 (6 μM), DMSO for 24 hours and subjected to flow cytometry analysis for the stem cell markers CD34 (A), c-KIT (B), CD69 (C) and CD44 (D). E, F Q-RT-PCR analysis of HEL cell treated with UM171 (3 μM) and DMSO for expression of the stem cell markers CD34, c-KIT, CD69, CD44, ERG (E) and CD40, CD41, CXCL8 and GFI1 (F).

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