Fig. 3: The effect of TAZ on BMP9-induced expression levels of pivotal osteogenic markers in MSCs and MMCs. | Cell Death Discovery

Fig. 3: The effect of TAZ on BMP9-induced expression levels of pivotal osteogenic markers in MSCs and MMCs.

From: TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9

Fig. 3

Cells were treated with TAZ or si-TAZ, followed by treatment with BMP9. A–L The mRNA expression of RUNX2, OPN, OCN, DLX5, ID1, ID2, and ID3 were determined by qPCR. M–X The protein expression of RUNX2, OPN and OCN were detected by Western blot. The data are shown as mean ± SD for three separated experiments. (*P < 0.05, **P < 0.01, ***P < 0.001) RUNX2 runt-related transcription factor 2, OCN osteocalcin, OPN osteopontin, DLX5 Distal-less homeobox 5, OSX Osterix, ID Inhibitor of differentiation.

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