Fig. 1: AST improved the cognitive dysfunction of APP/PS1 mice in the step-down avoidance (SDA) test and the Morris water maze (MWM) test.
From: Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice
A, B Timelines of the mice SDA and MWM test. C, D The step-down latency and the number of errors of mice in the SDA test. E The escape latency of mice to arrive at the platform during the positioning navigation test in the MWM test (Day 1–5). F, G Time of mice to reach the target platform and swimming trajectory diagrams of mice during the space exploration in the MWM test (Day 6). H The number of mice crossing the target platform during the visible platform period in the MWM test (Day 7–8). Data were presented as mean ± SD, n = 7/group. *p < 0.05, **p < 0.01 and ***p < 0.001 vs WT group, #p < 0.05, ##p < 0.01 and ###p < 0.001 vs APP/PS1 group.
