Fig. 2: AST reduced hippocampal neuronal damage of APP/PS1 mice by HE and Nissl staining. | Cell Death Discovery

Fig. 2: AST reduced hippocampal neuronal damage of APP/PS1 mice by HE and Nissl staining.

From: Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice

Fig. 2

A HE staining aimed to observe the alterations of neuronal morphology in mice hippocampus. Scale bar = 100, 50 μm, respectively. B Nissl staining aimed to detect changes in the morphology of Nissl bodies in the mice hippocampus. Scale bar = 100, 25 μm, respectively. C The grade of neuronal damage in the hippocampus of mice. D Statistical analysis of the Nissl bodies in the hippocampus of mice. Data were presented as mean ± SD, n = 4/group. ***p < 0.001 vs WT group, #p < 0.05 and ##p < 0.01 vs APP/PS1 group.

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