Fig. 3: AST reduced Aβ aggregation in the APP/PS1 mice.
From: Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice
A Detection of SPs in the brain of mice by Th-S staining and immunofluorescent co-staining. Scale bar = 500 μm in the three columns of images, and scale bar = 100 μm in the last column of images. B Statistical analysis of the number of SPs in the brain of mice in the merged images at 5X magnification (scale bar = 500 μm) of A. C, D The Aβ and Aβ42 levels in the serum of mice were detected by ELISA. Data were presented as mean ± SD, n = 3/group. ***p < 0.001 vs WT group, ##p < 0.01 and ###p < 0.001 vs APP/PS1 group.
