Fig. 2: Differential expression analysis of the GSE69528, GSE46955, and GSE54514 datasets.
From: Repositioning linifanib as a potent anti-necroptosis agent for sepsis
A Venn diagram showing the overlapping DEGs in the three datasets. B Volcano plot shows significantly differentially expressed genes in the three datasets. Red and blue plots represent upregulated and downregulated genes, respectively, with (|log2FC | >0.7 and P-value<0.05). Black plots represent the genes with no significant difference. C Heatmap of the top 100 DEGs in three datasets. Each row represents a DEG, and each column represents a sample. The color ratio indicates the relative level of DEG expression: blue, lower than reference expression; red, higher than reference expression.
