Fig. 2: LOC105369504 suppresses CRC cell proliferation and metastasis mediated with EMT in vitro. | Cell Death Discovery

Fig. 2: LOC105369504 suppresses CRC cell proliferation and metastasis mediated with EMT in vitro.

From: LncRNA LOC105369504 inhibits tumor proliferation and metastasis in colorectal cancer by regulating PSPC1

Fig. 2

A, B The effect of LOC105369504 on proliferation in RKO and HCT-116 cells transfected by LV-NC or LV-LOC105369504 through the CCK-8 assay. C Colony formation analyses for CRC cells after LOC105369504 was overexpressed. D, E Transwell analysis was applied for determining the CRC migration together with invasion after LOC105369504 was overexpressed. F Western blotting indicated increased epithelial marker expression and attenuated mesenchymal marker expression in the CRC cells transfected with LV-LOC105369504. All the data are expressed as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.

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