Fig. 3: CircMYBL2 promoted BC growth and liver metastasis. | Cell Death Discovery

Fig. 3: CircMYBL2 promoted BC growth and liver metastasis.

From: Hsa_circ_0060467 promotes breast cancer liver metastasis by complexing with eIF4A3 and sponging miR-1205

Fig. 3

MDA-MB-231 cells with stable luciferase expression were infected with LV-circMYBL2 or LV-vector and then injected into BALB/c nude mice. A In vivo optical imaging system was used to observe xenograft tumors in the indicated groups. B, C Representative images of xenograft tumors in the indicated groups. D Xenograft tumor weight in the indicated groups. E Xenograft tumor volumes were measured and calculated on the indicated days. Tumor volume was measured as (width2/2 × length). F The number of metastatic nodules in the livers of mice was calculated. G Hepatic metastases of BC hemi-spleen models in the indicated groups were collected and monitored by an in vivo optical imaging system. H The livers in the indicated groups were stained with H&E. All data were expressed as the mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001.

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