Fig. 2: The process and regulation of autophagy in PH.
From: Molecular regulation and therapeutic implications of cell death in pulmonary hypertension
Pulmonary hypertension can be alleviated by activating or inhibiting the autophagy of pulmonary vascular cells. Studies on the relevant mechanisms involve all aspects of the autophagy process, which is mainly regulated through the mTOR pathway. Red represents the enabler, and green represents the inhibitor.
