Fig. 5: The combinatorial SVGs in neocortex and hippocampus.

A SVGs expressed in both neocortex and hippocampus after hippocampus appearance. B SVGs mainly expressed in neocortex in the development. C SVGs mainly expressed in hippocampus in the development. D The higher-resolution IHC presentation for neocortex and hippocampus at P0. E The Nr4a2 expression patterns at E15.5 and P0. F The joint hotspot analysis among three genes Satb2, Nr4a2, and Zbtb20. In (A), (B), (C), and (E), the color schemes in SVG clusters and spatial transcriptomics are similar to that in Fig. 3A. In (F), the hotspot colors for different gene combinations are shown in the top legend.