Fig. 2: Infectious and proliferative capabilities of SARS-CoV-2 in HK2 and HUEhT cells. | Cell Death Discovery

Fig. 2: Infectious and proliferative capabilities of SARS-CoV-2 in HK2 and HUEhT cells.

From: Inhibition of Toll-like receptor 4 and Interleukin-1 receptor prevent SARS-CoV-2 mediated kidney injury

Fig. 2

A Relative amounts of SARS-CoV-2 RNA within HK2 and HUEhT cells 0–71 h after incubation of SARS-CoV-2 solution. The relative amount of viral RNA was quantified by real-time RT-PCR (each group, n = 4). One-way ANOVA with Dunnett’s multiple comparisons tests (control; 0 h) was performed for statistical analyses, and significance was defined as **P < 0.01, ***P < 0.001, ****P < 0.0001. B Virus recovery within VeroE6/TMPRSS2 cell. Cytopathic effects were evaluated in VeroE6/TMPRSS2 cells in response to supernatants or cell lysates of VeroE6/TMPRSS2, HK2, and HUEhT cells incubated with SARS-CoV-2. C Immunostaining of SARS-CoV-2 N proteins in SARS-CoV-2-inoculated-VeroE6/TMPRSS2 cells, HK2 cells, and HUEhT cells (1, 24 h after incubation). Green; SARS-CoV-2 N protein. Blue; DAPI. The scale bar is 100 μm.

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