Fig. 1: Morphological changes of human glioblastoma cells induced by NeuroD4.

A Schematic representation of the cell reprogramming process. B, C Rapid morphological changes of U251 and KNS89 cells were observed upon ectopic expression of NeuroD4. The control group was infected with GFP-expressing virus. Higher magnification views of the boxed regions are also depicted. Dpi: days after infection; GM: medium for glioblastoma cells; NM: medium for neuronal induction. Scale bar: 200 µm.