Fig. 1: Compound 6j significantly inhibited liver cancer cell proliferation.
From: Sophoridine derivative 6j inhibits liver cancer cell proliferation via ATF3 mediated ferroptosis
A Structure of 6j. B IC50 of 6j against six liver cancer cell lines (n = 3). C Compound 6j suppressed colony formation of MHCC-97H and HepG2 cells in a dose dependent manner (n = 3). D Inhibitors of apoptosis, autophagy, and necrosis could not alleviate 6j induced cell proliferation inhibition (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001.
