Fig. 7: Knockdown of ATF3 attenuated 6j induced ferroptosis and cell proliferation inhibition.
From: Sophoridine derivative 6j inhibits liver cancer cell proliferation via ATF3 mediated ferroptosis
RNAi with ATF3 siRNA decreased 6j induced accumulation of Fe2+ (A), MDA (B), and ROS (C) (n = 3). D RNAi with ATF3 alleviated 6j induced cell viability decreasing (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001.
