Fig. 1: PGC-1α expression is significantly down-regulated in fibrotic liver of I/R mice. | Cell Death Discovery

Fig. 1: PGC-1α expression is significantly down-regulated in fibrotic liver of I/R mice.

From: PGC-1α inhibits M2 macrophage polarization and alleviates liver fibrosis following hepatic ischemia reperfusion injury

Fig. 1

A H&E, Sirus red staining and immunohistochemistry analyses of Collagen I, α-SMA and PGC-1α expression in liver tissues of mice at 2 and 4 weeks post I/R. B, C Western blot and RT-qPCR analyses of the relative levels of Collagen I, α-SMA and PGC-1α expression in liver tissues of mice at 2 and 4 weeks post I/R. Data are representative images or shown as mean ± SD of each group (6–10/group) from at least three separate experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

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