Table 1 Combination indices (CI) for aspirin and lenvatinib.

From: Synergistic antitumor efficacy of aspirin plus lenvatinib in hepatocellular carcinoma via regulating of diverse signaling pathways

Cell Line

Lenvatinib (μM)

Aspirin (mM)

CI

Synergy

HepG2

5

5.959

0.895

+

10

3.325

0.761

++

15

1.449

0.717

++

Hepa1-6

5

4.957

0.873

+

10

2.767

0.758

++

15

1.288

0.741

++

  1. Based on the detailed CI values, the synergy strength is displayed with graded symbols. “+” indicates slight synergism; “++” indicates moderate synergism; “+++” indicates strong synergism.