Table 2 List of selected sDCTR-miRNAs validated targets.
Targets | sDCTR-miRNA | Biological processes/pathways |
|---|---|---|
FOXO3 | miR-96-5p | Proliferation/apoptosis escape |
CDKN1A | miR-96-5p | Proliferation/apoptosis escape |
PPP1R12A | miR-96-5p | Proliferation/apoptosis escape |
DDIT3 | miR-96-5p | Proliferation/apoptosis escape |
TIMP1 | miR-96-5p | Migration/invasion |
PDCD4 | miR-183-5p | Proliferation/apoptosis escape |
PPP2CB | miR-183-5p | Proliferation/apoptosis escape |
PPP2R4 | miR-183-5p | Proliferation/apoptosis escape |
AKAP12 | miR-183-5p | Proliferation/apoptosis escape; Migration/invasion |
MORF4L1 | miR-183-5p | Proliferation/apoptosis escape; Migration/invasion |
TMEM170B | miR-183-5p | Proliferation/apoptosis escape; Migration/invasion |
TXNIP | miR-183-5p | Proliferation/apoptosis escape; Regulation of oxidative stress |
BNIP3 | miR-210-3p | Proliferation/apoptosis escape |
IGFBP3 | miR-210-3p | Proliferation/apoptosis escape; Migration/invasion; IGF signaling |
CDK10 | miR-210-3p | Proliferation/apoptosis escape; Migration/invasion |
SDHD | miR-210-3p | Mitochondrial metabolism; Hipoxia (HIF-1α signaling) |
ISCU | miR-210-3p | Mitochondrial metabolism; Hipoxia (HIF-1α signaling) |
FOXO1 | miR-96-5p miR-183-5p | Proliferation/apoptosis escape |
ZFP36L1 | miR-96-5p miR-183-5p | Proliferation/apoptosis escape; Migration/invasion |
INSIG1 | miR-183-5p miR-210-3p | Proliferation/apoptosis escape; Migration/invasion; Lipogenesis |
