Fig. 1: The complement system was related to Rituximab resistance in Farage cells. | Cell Death Discovery

Fig. 1: The complement system was related to Rituximab resistance in Farage cells.

From: METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells

Fig. 1

A The survival rates of Rituximab-sensitive Farage (Farage/S) and Rituximab-resistant Farage (Farage/R) cells at different concentrations of Rituximab, and the IC50 value. B, C Apoptotic cells during treatment with 20 μg/mL Rituximab were detected by flow cytometry and TUNEL staining. D The proliferation of cells treated with 20 μg/mL Rituximab was detected by the colony formation assay. E Members of the complement pathway. F C3 chains expressed during treatment with 20 μg/mL Rituximab were detected by western blotting. G, H Recognition units of the complement system (C1q, C1r, and C1s), were detected by western blotting. ns, not significant; ***p < 0.001.

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