Fig. 7: Knockdown of METTL3 increased the Rituximab sensitivity of Farage/R cells in vivo. | Cell Death Discovery

Fig. 7: Knockdown of METTL3 increased the Rituximab sensitivity of Farage/R cells in vivo.

From: METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells

Fig. 7

A Mice were subcutaneously injected with R-shCtrl or R-shMETTL3 cells and then treated with Rituximab. On day 27 after xenograft, the mice were sacrificed and the tumor tissues were collected. B Tumor growth curves were plotted with the tumor size measured every 4 days. C The weights of the collected tumors. D, E The expression of C1qA in tumor tissues. F C3 chains were detected by western blotting. G, H Caspase-3 and Ki67 expression in tumor tissue was detected by immunohistochemistry. ***p < 0.001.

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