Fig. 8: Knockdown of YTHDF2 increased the Rituximab sensitivity of Farage/R cells. | Cell Death Discovery

Fig. 8: Knockdown of YTHDF2 increased the Rituximab sensitivity of Farage/R cells.

From: METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells

Fig. 8

A–C The expression of YTHDF2 and C1qA in Farage/R cells with YTHDF2 knockdown (R-shYTHDF2) and in control cells (R-shCtrl). D The level of m6A-modified C1qA. E Cell survival rates and the IC50 value of Rituximab. F The proliferation of cells being treated with 20 μg/mL Rituximab was detected by the colony formation assay. G C3 chains expressed during treatment with 20 μg/mL Rituximab were detected by western blotting. H The proportions of apoptotic cells during treatment with 20 μg/mL Rituximab were detected by flow cytometry. ***p < 0.001.

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