Fig. 2: Frequencies of RIOK1 misexpression, amplification or alterations across the cancer spectrum.
From: The RioK1 network determines p53 activity at multiple levels
A Percentage of cancers that misexpress RIOK1. n = number of cases. B Percentage of cancers carrying specific alterations in RIOK1. n = number of cases. C Percentage of cancers that only overexpress RIOK1 and of those that also carry mutations in TP53. n = number of cases, p-values indicate the statistical likelihood of RIOK1 overexpression and TP53 mutations coinciding in the same cancer. D Percentage of cancers with amplified RIOK1 and of those that also carry mutations in TP53. n = number of cases, p-values indicate the statistical likelihood of RIOK1 amplification and TP53 mutations coinciding in the same cancer. The data in panels A, B, C, and D were obtained from the cBioPortal for Cancer Genomics v5.4.3 [3].
