Fig. 1: Generation of ARK5 knockout (ARK5‐KO) clonal cells with CRISPR/Cas9 system involving human myeloma cell lines, KMS-11, and Sachi. | Cell Death Discovery

Fig. 1: Generation of ARK5 knockout (ARK5‐KO) clonal cells with CRISPR/Cas9 system involving human myeloma cell lines, KMS-11, and Sachi.

From: ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells

Fig. 1

A Western blot analysis for MAF, MAFB, and ARK5 expression in the MM cell lines. GAPDH was used as an internal control. B A single guide RNA sequence was developed against exon 1 of ARK5 locus. C ARK5 protein expression was revealed via western blot analysis. D The genomic sequence analysis of ARK5 in KMS-11 and Sachi-KO clonal cells was compared with that of parent cells.

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