Fig. 4: Effects of ARK-5-KO on mitochondrial morphology in myeloma cells. | Cell Death Discovery

Fig. 4: Effects of ARK-5-KO on mitochondrial morphology in myeloma cells.

From: ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells

Fig. 4

A, B Staining of mitochondria and nuclei was done with MitoTracker Red and Hoechst (blue), respectively, in human myeloma cells. ARK5-KO cells exhibited mitochondrial fusion, while ARK5-wild type (ARK5-WT) cells showed mitochondrial fission. ARK5-WT showed a spotty distribution of mitochondria (upper panel). Conversely, ARK5-KO cells demonstrated mitochondrial fusion (lower panel) in both myeloma cell lines, KMS-11 and Sachi. The right panel shows the magnification of the left panel.

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