Fig. 2: P6-induced THP-1 cells altered the morphology and enhanced macrophage surface markers. | Cell Death Discovery

Fig. 2: P6-induced THP-1 cells altered the morphology and enhanced macrophage surface markers.

From: Generation of a new therapeutic d-peptide that induces the differentiation of acute myeloid leukemia cells through A TLR-2 signaling pathway

Fig. 2

A THP-1 cells were stimulated with P6 or PMA for 48 h, and empty vector-treated cells were used as a negative control. The suspended cells were gently removed through a PBS wash. The morphological features were then visualized by phase contrast microscopy. B May-Grünwald Giemsa staining of THP-1 cells treated with either PMA, P6 or an empty vector for 48 h. C, D Cell surface markers CD11b (C) and CD14 (D) were detected by FACS after 48 h incubation with P6. The results are shown as the mean and SEM. ***P < 0.001 (Kruskal–Wallis test). MFI median fluorescent intensity. Data are from 6 independent experiments.

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