Fig. 7: The ROR1 expression correlated with the expression of cancer stem cell-related genes in breast cancer cells.

A Comparison of breast cancer stem cell-related genes between ROR1-high and -low groups (n = 38). The boxes represent the interquartile range (25th to 75th), and the horizontal lines inside the boxplot indicate the median. Whiskers on top and bottom indicate the maximum and minimum values of the data. The ROR1-high group was defined as tumors with an ROR1 expression value higher than the median for all samples. The ratios were calculated by dividing the mRNA expression value of the high group by the expression value of the low group. P values were calculated using the Wilcoxon signed rank test. ALDH1 expression in B si-ROR1, and C si-lncRNA DLEU2 cells. The expression differences between si-control and si-ROR1 and si-lncRNA DLEU2 were compared. P value was calculated using Student’s t-test. The BMI1 mRNA level in parental, si-control, and si-ROR1 (D) and si-lncRNA DLEU2 (E) The expression difference between si-control, si-ROR1, and si-lncRNA DLEU2 were compared. P value was calculated using Student’s t-test.