Table 2 Functional analysis of antigen binding properties.

From: Antibody and antibody fragments site-specific conjugation using new Q-tag substrate of bacterial transglutaminase

Antibody

Kd (pM)

Trastuzumab-Qtag2

92.1 ± 3.1

TrastuzumabKdel-Qtag2

66.2 ± 2.9

TrastuzumabKdel-Qtag2-PEG4-VC-MMAE

85.3 ± 2.8

  1. Biacore surface plasmon resonance analysis of anti-human IgG FC captured (AHC biosensor) recombinant antibodies and conjugates with rhu-HER2 protein. KD, affinity constant.
Back to article page