Fig. 4: Knockdown of Fscn2 in HEI-OCI cells resulted in low cell proliferation ability and migration rate. | Cell Death Discovery

Fig. 4: Knockdown of Fscn2 in HEI-OCI cells resulted in low cell proliferation ability and migration rate.

From: Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice

Fig. 4

A Cell viability was assessed by CCK-8 assays. B, C The migration assay was performed to evaluate the migration ability of cells. Scale bar, 100 μm. D The levels of PARVB, ILK, p-ILK, AKT, p-AKT, cleaved Caspase9 and Bcl-2 in the Fscn2 knockdown cells were detected by Western blot. E–H The four panels on the right side show the results of densitometric analysis of the bands on Western blots. Data are represented as means ± SEM. *P < 0.05; **P < 0.01.

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