Fig. 5: Overexpression of Fscn2 in HEI-OC1 cells (o/e-Fscn2 cells) lead to increment of cell proliferation ability and cell migration rate. | Cell Death Discovery

Fig. 5: Overexpression of Fscn2 in HEI-OC1 cells (o/e-Fscn2 cells) lead to increment of cell proliferation ability and cell migration rate.

From: Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice

Fig. 5

A Cell viability was assessed by CCK-8 assays. B, C The migration assay was performed to evaluate the migration ability of cells. D The levels of PARVB, ILK, p-ILK, AKT, p-AKT, cleaved Caspase9 and Bcl-2 in Fscn2 overexpression cell were tested by Western blot. E–H The four panels on the right side are the results of densitometric analysis of the bands on Western blots. Data are represented as means ± SEM. *P < 0.05; **P < 0.01; ns no significance. Scale bar, 100 μm.

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