Fig. 1: A cuff and high-fat diet caused the artery lumen to narrow, leading to ED in rats.

A H&E staining of the common iliac artery; scale bar: 200 μm. B Ratio of the intima area to the lumen area. C ICP curves for each group. The red line indicates 60 s of electrical stimulation of the cavernous nerve. D Ratio of the max ICP to the MAP. E Real-time observation of penile blood filling during erections in each group of rats. F Ratio of penile to rectal temperature. The data are displayed as the mean ± standard deviation (n = 6). ****p < 0.0001.