Table 1 Demographic and clinical characteristics of ESCC patients and healthy volunteers in discovery cohort.
Characteristics | ESCCa patients | Healthy volunteers | p value |
|---|---|---|---|
Total Number | 81 | 81 | |
Gender (male/female) | 60/21 | 63/18 | 0.713 |
Age (mean ± SDb, year) | 62.49 ± 8.1 | 59.25 ± 7.8 | 0.010 |
BMIc (mean ± SDb) | 23.45 ± 3.2 | 24.61 ± 3.0 | 0.018 |
Smoker, n (%) | 37 (45.7) | 35 (43.2) | 0.874 |
Drinker, n (%) | 35 (43.2) | 32 (39.5) | 0.750 |
TNMd, n (%) | |||
0/I | 5 (6.2) | — | |
II | 38 (46.9) | — | |
III | 32 (39.5) | — | |
IV | 6 (7.4) | — | |
Clinical T stage, n (%) | — | ||
T0–T2 | 18 (22.2) | — | |
T3–T4 | 63 (77.8) | — | |
Clinical N stage, n (%) | — | ||
N0 | 43 (53.1) | — | |
N1–N3 | 38 (46.9) | — | |
Tumor size, n (%) | — | ||
<5 cm | 35 (43.2) | — | |
≥5 cm | 46 (56.8) | — | |
Tumor location, n (%) | — | ||
Upper thoracic | 3 (3.7) | — | |
Middle thoracic | 59 (72.8) | — | |
Lower thoracic | 19 (23.5) | — | |
Differentiation grade, n (%) | — | ||
G1 | 20 (25.0) | — | |
G2 | 35 (43.8) | — | |
G3 | 25 (31.2) | — |
