Fig. 6: Apoptotic cell death induced by PL in KG-1a cells. | Cell Death Discovery

Fig. 6: Apoptotic cell death induced by PL in KG-1a cells.

From: Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling

Fig. 6

A Representative flow cytometry dot plots. B Quantification of apoptosis in KG-1a cells after 12, 24, 48 and 72 h of treatment with PL. Quantification of live (YO-PRO-1- and PI-negative cells), apoptotic (YO-PRO-1-positive cells) and dead (YO-PRO-1- and PI-positive cells) KG-1a cells. Vehicle (0.2% DMSO) was used as a negative control (CTL) and doxorubicin (DOX, 1 µM) was used as a positive control. The data are shown as the mean ± S.E.M. of three independent experiments carried out in duplicate. *p < 0.05 compared with CTL by one-way ANOVA followed by Dunnett’s multiple comparisons test.

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