Fig. 2: CKS1 induces rapid cell death in multiple cancer cell lines but not in non-cancerous cell lines. | Cell Death Discovery

Fig. 2: CKS1 induces rapid cell death in multiple cancer cell lines but not in non-cancerous cell lines.

From: Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth

Fig. 2

A Cell viability of 4T1 cells after CKS1 treatment was measured by a real-time cell analyzer (RTCA). The vertical, dotted line indicates the time of peptide addition, and solid lines and the shaded areas show the mean and the standard error of the technical replicates, respectively. Representative of N = 3. B–E The cell viability and the release of LDH were measured after the cells were treated with the indicated concentration of CKS1 for 6 h. The blue data points and the red data points show the cell viability and the release of LDH, respectively. The release of LDH in the supernatant was measured by the CyQUANT LDH cytotoxicity assay and was normalized to the amount of LDH released from cells treated with lysis buffer. The curves show the dose-response curves fitted to the observed data. Each data point shows the technical replicate of each experiment. Representative of N = 3 independent experiments.

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