Fig. 5: Regulation of WNT/β-catenin signaling by TM7SF2 via CPT1A in cervical cancer. | Cell Death Discovery

Fig. 5: Regulation of WNT/β-catenin signaling by TM7SF2 via CPT1A in cervical cancer.

From: TM7SF2-induced lipid reprogramming promotes cell proliferation and migration via CPT1A/Wnt/β-Catenin axis in cervical cancer cells

Fig. 5

A The gene set enrichment analysis (GSEA) was exerted to explore the signaling pathways related to CPT1A. B, C Western blotting analysis of WNT/β-catenin signaling pathway-related protein expression after TM7SF2 overexpression and TM7SF2 knockdown in C33A cells. D, E Western blotting analysis of WNT/β-catenin signaling pathway-related protein expression after TM7SF2 overexpression and TM7SF2 knockdown in SiHa cells. F Western blotting analysis of WNT3A and β-catenin protein expression in TM7SF2-overexpressed C33A cells after MSAB treatment. G Western blotting analysis of the effect of CPT1A-overexpressed regulated the protein expression of WNT3A, β-catenin and c-Myc in TM7SF2-slienced C33A cells. H Western blotting analysis of WNT3A and β-catenin protein expression in TM7SF2-overexpressed SiHa cells after MSAB treatment. I Western blotting analysis of the effect of CPT1A-overexpressed regulated the protein expression of WNT3A, β-catenin in TM7SF2-slienced SiHa cells.

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