Fig. 3: MT markedly alleviates ferroptosis in macrophages after LPS stimulation.
From: Melatonin alleviates septic ARDS by inhibiting NCOA4-mediated ferritinophagy in alveolar macrophages
A–C The FTH1 and GPX4 protein levels were detected by western blot. Cell proliferation detected by the EdU assay kit was observed under a fluorescence microscope (D) and statistics as shown in (E). Lipid peroxidation levels detected by the C11 BODIPY assay kit were observed under a fluorescence microscope (F) and statistics as shown in (G). Intracellular GSH (H), MDA (I), and Fe2+ (J) contents were detected by corresponding assay kits. Data are expressed as mean ± SD (n = 6), * p < 0.05, **p < 0.01 indicate significant differences from each group, NS indicates no significance.
