Fig. 4: MT inhibits RAW264.7 cell ferroptosis via MT2.
From: Melatonin alleviates septic ARDS by inhibiting NCOA4-mediated ferritinophagy in alveolar macrophages
Intracellular GSH (A), MDA (B), and Fe2+ (C) contents were detected by corresponding assay kits. Cell proliferation detected by the EdU assay kit was observed under a fluorescence microscope (H) and statistics as shown in (D). E–G The FTH1 and GPX4 protein levels were detected by western blot. Data are expressed as mean ± SD (n = 6), *p < 0.05, **p < 0.01 indicate significant differences from each group, NS indicates no significance.
