Fig. 4: Regulation of USP3 expression in different levels.
From: Ubiquitin specific peptidase 3: an emerging deubiquitinase that regulates physiology and diseases
The formation of a transcriptional activation complex involving ALYREF and MYCN and Smo promote the transcription of USP3 in the DNA level; related ceRNA network of USP3 and RNA-binding proteins regulate USP3 expression in the mRNA level; PEITC (Phenethylisothiocyanate, a DUB inhibitor) and PARP1 (poly-ADP-ribose polymerase 1, a positive role) can influence USP3 (drawn by Figdraw) in the protein level.
