Fig. 5: Lactulose to mannitol ratio. | Cell Death Discovery

Fig. 5: Lactulose to mannitol ratio.

From: Current understanding of the interplay between extracellular matrix remodelling and gut permeability in health and disease

Fig. 5

The lactulose to mannitol ratio (LMR) is an indicator of barrier integrity. Lactulose is a slightly absorbed disaccharide that undergoes elimination, while mannitol is a polyol highly absorbed in the intestinal mucosa. Higher levels of LMR suggest the presence of a functional and integer intestinal barrier, however, when this ratio is lower, barrier disruption is expected [136]. Created with BioRender.com.

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