Fig. 2: SNHG1 knockdown inhibited RCC cell proliferation, migration and invasion. | Cell Death Discovery

Fig. 2: SNHG1 knockdown inhibited RCC cell proliferation, migration and invasion.

From: An oncogenic role of lncRNA SNHG1 promotes ATG7 expression and autophagy involving tumor progression and sunitinib resistance of Renal Cell Carcinoma

Fig. 2

ACHN and 786-O cells were transfected with sh-NC or sh-SNHG1 for 48 h. After that, CCK-8 and EdU assays were performed to determine cell viability (A) and proliferation (B). Scale bar, 50 μm. Transwell assay was utilized to assess cell migration and invasion (C). Scale bar, 100 μm. D RT-qPCR was used to detect EMT-related markers (E-cadherin, N-cadherin, Vimentin) in ACHN and 786-O cells with sh-NC or sh-SNHG1. Values are mean ± SD. Experiments were repeated at least three times. *P < 0.05, **P < 0.01.

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