Fig. 5: ATG7 was essential for SNHG1-mediated malignant behaviors of RCC cells. | Cell Death Discovery

Fig. 5: ATG7 was essential for SNHG1-mediated malignant behaviors of RCC cells.

From: An oncogenic role of lncRNA SNHG1 promotes ATG7 expression and autophagy involving tumor progression and sunitinib resistance of Renal Cell Carcinoma

Fig. 5

RCC cell resistant strains were transfected with sh-SNHG1, pcDNA3.1-ATG7 and negative controls. After 48 h transfection, (A) RT-qPCR was used to test ATG7 expression in RCC cell resistant strains with sh-SNHG1 and pcDNA3.1-ATG7. B CCK-8 analysis was performed to determine cell viability in different groups. C Transwell assay was utilized to assess cell migration and invasion in different groups. Scale bar, 100 μm. D RT-qPCR detection of EMT-related markers in different groups. Results expressed as mean ± SD. Experiments were repeated at least three times. **P < 0.01, ***P < 0.001.

Back to article page