Fig. 8: Another apoptosis marker caspase 3 and caspase 9 was activated in kri1l−/− mutants.
From: Mutant kri1l causes abnormal retinal development via cell cycle arrest and apoptosis induction

A–F Representative cleaved caspase3 immunofluorescence images for frozen embryo eye sections from sibling A–C and kri1l−/− mutants D–F at 4 dpf. The zoom section had shown in A′-F′. G Statistical analysis of cleaved caspase3 + cells in sibling and kri1l−/− mutants. H–M Representative cleaved caspase9 immunofluorescence images for frozen embryo eye sections from sibling H–J and kri1l−/− mutants K–M at 4 dpf. The zoom section had shown in H′–M′. N Statistical analysis of cleaved caspase9 + in sibling and kri1l−/− mutants. Error bars represent the standard deviation (SD). *, P < 0.05; **, P < 0.01; ***, P < 0.001. Scale bar, 50 μm.