Fig. 3: RNA-seq and bioinformatic analysis. | Cell Death Discovery

Fig. 3: RNA-seq and bioinformatic analysis.

From: Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCδ mediates endothelial apoptosis in diabetic wound healing

Fig. 3

A The number of DEGs satisfying fold changes ≥1.2 and q value ≤ 0.05. B, C The volcano map and heat map of 424 DEGs. Two genes colored green were chosen for subsequent study. D–F GO (GO_CC, GO_MF, GO_BP) analysis of 424 DEGs. Significantly enriched biological pathways were colored green. G KEGG pathway enrichment of 424 DEGs. Enriched metabolic pathways were colored green. H The heat map of genes encoding the enzymes catalyzing the cholesterol synthesis pathway. Two genes colored green were significantly differentially expressed in two groups.

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