Fig. 8: HMGCR inhibition accelerated wound healing of STZ-induced diabetic mice. | Cell Death Discovery

Fig. 8: HMGCR inhibition accelerated wound healing of STZ-induced diabetic mice.

From: Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCδ mediates endothelial apoptosis in diabetic wound healing

Fig. 8

A, B Images and quantification of wound area in rosuvastatin calcium-treated group and control group. C The free cholesterol level of skin tissue after rosuvastatin calcium treatment for 12 days. Each experiment was replicated at least thrice and representative images were shown. Quantification was done using a two-tailed unpaired Student’s t test. The results are presented as the mean ± SEM, *p < 0.05, **p < 0.01, ****p < 0.0001 vs controls.

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