Fig. 7: β-catenin inhibitor ICG-001 promoted intra-tumoral DC infiltration and suppressed LN metastasis of mIC-23 cells. | Cell Death Discovery

Fig. 7: β-catenin inhibitor ICG-001 promoted intra-tumoral DC infiltration and suppressed LN metastasis of mIC-23 cells.

From: Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma

Fig. 7

A Treatment schedule for β-catenin inhibitor ICG-001 in mIC-23 footpad tumor model. B In vivo bioluminescence imaging was used to monitor primary footpad tumor (black arrow) and popliteal LN metastasis (red arrow). C Proportion of popliteal LN metastasis from indicated groups. Representative immunofluorescence staining images of CD45+ CD11c+ DCs (D) and corresponding statistics (E) in mIC-23 footpad tumors from indicated groups. F Quantification of CD8+ T cells in mIC-23 footpad tumors from indicated groups.

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