Fig. 3: Y RNA processing involves ribonuclease and its inhibitor, responsible for caspase 3 dependency.
From: PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation
A S-100 fractions separated by ammonium sulfate fractionation (left). The ratio of ASR/Y3 RNA was calculated and plotted in a bar graph (right). B Ammonium sulfate fraction (50–60%) separated by IEC. RNase activity was detected in fractions e and f, which were defined as RNase fraction (R.F.) (left). The ratio of ASR/Y3 RNA was calculated and plotted in a bar graph (right). C RNase activity in the R.F.re mixed with other fractions with or without caspase 3 (left). The ratio of ASR/Y3 RNA was calculated and plotted in a bar graph (right). Similar results were obtained in two independent experiments.
