Fig. 3: m6A modification in various cells.
From: Progression of m6A in the tumor microenvironment: hypoxia, immune and metabolic reprogramming
m6A methylation is regulated by the m6A methyltransferase complex (writers), m6A demethylase (erasers), and m6A binding protein (readers). Regulators associated with m6A methylation affects activation and function of DC cells (A), function of B cell and Treg (B, D), homeostasis and function of NK cell (C), polarization and plasticity of TAM (E), M1 and M2 (F, G), differentiation and function of TA-MSC (H).
