Fig. 2: Bithionol reduces the number of AML stem-like cells. | Cell Death Discovery

Fig. 2: Bithionol reduces the number of AML stem-like cells.

From: Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis

Fig. 2

Immunophenotypic analysis of the myeloid lineage markers CD13 (A) and CD33 (B) and the AML progenitor/stem markers CD34 (C), CD38 (D) and CD123 (E) in bithionol-treated KG-1a cells after 48 h of incubation. The vehicle (0.2% DMSO) was used as a negative control (CTL). The data are shown as the mean ± SEM of three biological replicates carried out in duplicate. *p < 0.05 compared with CTL by one-way ANOVA followed by Dunnett’s multiple comparisons test.

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