Fig. 5: Cell cycle progression in KG-1a cells after treatment with bithionol. | Cell Death Discovery

Fig. 5: Cell cycle progression in KG-1a cells after treatment with bithionol.

From: Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis

Fig. 5

Representative histograms after 12 (A), 24 (B), 48 (C), and 72 (D) h of treatment. Percentages of cells in sub-G0/G1 (E), G0/G1 (F), S (G), and G2/M (H) after different incubation periods with bithionol. Vehicle (0.2% DMSO) was used as a negative control (CTL), and doxorubicin (DOX, 1 µM) was used as a positive control. The data are shown as the mean ± S.E.M. of three biological replicates carried out in duplicate. *p < 0.05 compared with CTL by one-way ANOVA followed by Dunnett’s multiple comparisons test.

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