Fig. 4: PLK4 promoted the EC progression.

A CCK8 assay in PLK4-overexpressed and KIFC1-knockdown EC cell lines (HEC-1A and Ishikawa). B Colony formation assay in PLK4-overexpressed and KIFC1-knockdown EC cell lines (HEC-1A and Ishikawa). C Transwell assay and quantitative analysis of migratory and invasive abilities of PLK4-overexpressed and KIFC1-knockdown EC cell lines (HEC-1A and Ishikawa) (scale bar: 100 μm). **P < 0.01, ##P < 0.01.